Abstract

ASSESSMENT OF PRESCRIBING PATTERN AMONG TYPE-II DIABETES MELLITUS PATIENTS IN A TERTIARY CARE HOSPITAL

Saurabh Saklani*, Ankit Goel, Poonam Rishishwar and Sanjay Rishishwar

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Abstract

In India, Diabetes Mellitus is probably becoming a pandemic. India's diabetes population is predicted to grow from approximately 69.2 million in 2015 to 123.5 million in 2040. It can be treated by various types of Antidiabetic Drugs that has not only beneficial effect; it also causes adverse drug reactions. This was a prospective, observational study carried out among patients of Type II Diabetes Mellitus in a tertiary care hospital of Dehradun to evaluate prescription pattern monitoring studies (PPMS). Study was carried out by reviewing prescription of 180 Type II Diabetes Mellitus patients. Out of 180 patients 55.5% were male and 44.5% were females. The majority of the patients were in age group of 41 - 60 years (70.5%). Among 180 patients, 48.33% were alcoholic, 51.67% were non-alcoholic. Most commonly prescribed drugs were Biguanides (42.73%), followed by Sulfonylureas (20.88%) and DPP-4 inhibitor (19.18%). Most commonly prescribed Biguanides drugs were Metformin (100%), Sulfonylureas drugs were Glimepiride (93.10%) and DPP-4 inhibitor drugs were Teneligliptin (53.17%). Among all drugs prescribed, 35.20% was prescribed as monotherapy and remaining 64.80% was prescribed as combination therapy. Most commonly prescribed combination drug therapy was Metformin + Vildagliptin (31.67%). Due to high value of average number of drugs per patient, problem of concern was polypharmacy which requires the control through rational prescribing practices the drugs prescribing practices in the Type II Diabetes Mellitus treatment.

Keywords: Type II diabetes Mellitus, Prescribing pattern, Biguanides, Sulfonylureas, Polypharmacy.