Abstract

TYPE 2 DIABETICS MELLITUS CURED BY METFORMIN

Kiran Santosh Kapgate* and Upadesh B. Lade

Abstract

Metformin, a widely prescribed oral hypoglycemic agent, is used to treat type 2 diabetes by reducing appetite, inhibiting hepatic gluconeogenesis, and increasing glucose uptake by peripheral tissues. Metformin can prevent complications from high blood glucose but can negatively impact renal functions in T2DM patients, leading to chronic kidney disease. It can accumulate and cause lactic acidosis. Careful use is advised in elderly patients, those with trauma, fever, surgery, heart failure, or impaired kidney or liver functions. Moreover, the costeffectiveness of metformin has been established. Generally, metformin is an excellent choice both in the specialized setting and in primary health care.

Keywords: Diabetes mellitus, metformin, oral hypoglycemic agents, treatment, uses.