Abstract

DEVELOPMENT AND INVITRO CHARACTERIZATION OF PHYTOSOMES OF THE BOBGUNNIA MADAGASCARIENSIS WITH POOR BIOAVAILABILITY

Yash Nagar* and Dr. Chetan Singh Chauhan

Abstract

The study focuses on the creation and laboratory analysis of phytosomes produced from the Bobgunniamadagascariensis plant, which has medicinal benefits but is limited by its low absorption. The major goal is to boost the absorption of active phytoconstituents by the use of advanced drug delivery methods, especially phytosomes. The study uses multiple ways to make and measure the phytosomes, including liquid evaporation, lyophilization, and mechanical dispersion methods. The resultant phytosomal complexes are submitted to strict analysis methods, such as Fourier Transform Infrared Spectroscopy (FTIR), Transmission Electron Microscopy (TEM), and in-vitro drug release tests. The results show a considerable rise in the solubility and absorption of the active ingredients when enclosed in phytosomes compared to their free forms. Phytosomes show better stability, greater drug-trapping effectiveness, and longer drug-release patterns. These results indicate that the phytosomal preparation of Bobgunniamadagascariensis might serve as a valid method for beating the limits of traditional plant drug delivery systems, providing possible therapeutic benefits in the treatment of numerous diseases. In conclusion, the study gives proof that phytosomes may successfully boost the solubility of plant products, opening the door for future research and growth in this area. The successful application of phytosome technology in this study shows its promise as a feasible method for improving the delivery and effectiveness of plant-based treatments.

Keywords: Phytosomes show better stability, greater drug-trapping effectiveness, and longer drug-release patterns.