Abstract

A PROSPECTIVE OBSERVATION STUDY ON DIABETES COMPLICATION AND PRESCRIBING PATTERN OF ANTIDIABETIC AGENTS

Vrunda Dimpalbhai Chhatrala*, Megha Kamleshsinh Desai, Krupalsinh D Mahida, Dr. Divya G. Sonani and Dr. Surbhi Chitania

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Abstract

Background: Diabetes is one of the largest global health emergencies of this century, ranking among the top ten leading causes of mortality alongside diseases such as cardiovascular disease, respiratory disease, and cancer. India is one of the epicenters of the diabetes mellitus pandemic. Rapid socioeconomic development, demographic changes, and an increased genetic susceptibility among Indian individuals have led to an explosive rise in the prevalence of diabetes mellitus in India over the past several years. The risk of diabetes is influenced by ethnicity, age, obesity, physical inactivity, unhealthy diet, behavioral habits, genetics, and family history. The prevention and management of diabetes and its associated complications present a significant challenge in India due to several issues and barriers, including the lack of a multisectoral approach, insufficient surveillance data, lack of awareness regarding diabetes, its risk factors and complications, and limited access to healthcare settings and affordable medicine.[1] Methods: The prospective observational study was conducted over a period of 6 months at Venus Hospital Surat. Ethical clearance was obtained from the SDPC Institutional Ethics Committee. The data of 120 patients were collected and recorded in case report form based on inclusion and exclusion criteria. Results: Out of 120 patients, the majority were males (53%) and primarily aged between 61 and 70 years (42.5%). Hypertension (59.17%) was the most commonly found comorbid condition. Overall, monotherapy was more predominant than combination therapy, with most patients being treated with a single drug, metformin. Among those receiving insulin therapy, Insulin Human Actrapid was the most frequently prescribed (11.21%). Microvascular complications were more common than macrovascular complications. Conclusion: The results highlight, the study provides valuable insights into the prevalence of diabetes complications and the current prescribing patterns of anti-diabetic agents in our study population. It has been concluded that the selection of anti-diabetic drugs has changed only slightly compared to prior studies.

Keywords: Diabetes Mellitus, Antidiabetic Medications, Diabetes Complications.