Abstract

PHYSIOCHEMICAL ANALYSIS IN STANDARDIZATION OF SIDDHA POLYHERBAL FORMULATION KANA KUDINEER

Dr. S. Simal*, Dr. C. Shanmuga Priya and Dr. A. Satheesh Kumar

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Abstract

Introduction: Siddha Medicine, a precious gem in the treasury of Indian heritage, embodies the wisdom of the ages offering year compassionate and comprehensive approach to health and wellness. Siddha medicine emphasizes the use of natural remedies including plants minerals and metals to treat various ailments. Most of the Siddha medicines are effective but they have not been standardized yet. Standardization of Siddha Polyherbal formulation becomes essential to establish the monograph of the particular formulation along with this, it encompasses the Genuity, purity and safety of the preparations intended for usage in patients. “Kana Kudineer”(KK), a polyherbal formulation in Siddha medicine, is traditionally used to treat bronchial asthma, also known as Sooli Kanam. Asthma is a major non-communicable disease affecting both children and adults. Inflammation and narrowing of the small airways in the lungs cause asthma symptoms which can be any combination of cough, wheeze, shortness of breath and chest tightness. Aim and Objective: To standardize kana kudineer(KK) a siddha polyherbal formulation using physiochemical analysis and other analytical techniques such as HPTLC and TLC. Materials And Methods- Siddha poly herbal formulation “Kana kudineer”, Siddha drug mentioned in the textbook of Pillai Pini Maruthuvam part 2 which is used to treat childhood bronchial asthma. A scientific approach was undertaken to standardize the siddha polyherbal formulation KK by conducting a through physiochemical evaluation, HPTLC and TLC thereby ensuring the establishment of its quality and efficacy parameters. Results: The results obtained from physicochemical evaluation shows that the Total ash value of Kana kudineer (KK) was “3.5±0.26%”, in which the acid insoluble ash was “6.16±0.68%”, loss on drying at 105ºC of the formulation KK was noted to be “4.86±0.55” in which watersoluble extract value and alcohol soluble extract value was “23.13±2.41”, and “2.18±2.78” respectively. The pH value of the drug 7.52 which is indicates it is slightly alkaline(basic). HPTLC finger printing analysis of the sample reveals the presence of eight prominent peaks corresponds to the presence of eight components present with in it. Conclusion: The preliminary physiochemical analysis of the siddha drug KK provides a foundational fingerprint for future clinical studies, thereby facilitating the establishment of its safety, efficacy and quality parameters.

Keywords: Kana kudineer, polyherbal formulation, physiochemical analysis, HPTLC, Sooli kanam.