Abstract

NANOREVOLUTION: TRANSFORMING CANCER THERAPY THROUGH NANOTECHNOLOGY

Pavankumar P. Wankhade* Harshwardhan Prakash Mane, Rushikesh Balasaheb Patil, Anand Anil Jadhav and Vedantika Ramesh Salunkhe

Abstract

Nanotechnology has emerged as a promising avenue in cancer treatment, offering novel approaches to overcome the limitations of conventional therapies. This abstract provides an overview of recent advancements and future perspectives in the application of nanotechnology for cancer treatment. Nanoparticles, with their unique physicochemical properties, can be tailored to target tumors specifically, enhancing drug delivery while minimizing systemic toxicity. Moreover, nanotechnology enables the development of multifunctional platforms capable of simultaneous imaging, targeting, and therapy—paving the way for personalized medicine approaches. By incorporating targeting ligands, such as antibodies or peptides, nanoparticles can selectively home to cancer cells, enhancing therapeutic outcomes. Furthermore, nanotechnology plays a crucial role in overcoming drug resistance mechanisms through the delivery of combination therapies and targeted inhibition of specific pathways. Additionally, nanomaterial’s can enhance the efficacy of radiation therapy and photodynamic therapy by augmenting the delivery of therapeutic agents and sensitizing tumor cells to treatment. The integration of theranostic platforms, combining therapy and diagnostics, holds promise for real-time monitoring of treatment response and individualized therapy adjustment. Furthermore, advancements in nanotechnology have facilitated the development of novel immunotherapeutic approaches, such as cancer vaccines and immune checkpoint inhibitors, for more effective cancer treatment.

Keywords: Cancer, Nanotechnology, Gene Therapy, Immunotherapy, Active and Passive Targeting, Drug Delivery.