Abstract

A CONCEPTUAL REVIEW OF VRANAGRANTHI ACCORDING TO AYURVEDA AND CONTEMPORARY SCIENCE

Pooja Narayan Telangre*, Rakesh Kumar, Yogesh Kapse and Supriya Nirmal

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Abstract

Acharya vagbhata in Ashtanga sangraha has mentioned Vraṇa Granthi, while explaining the types of Granthi. As stated by vagbhata, Due to injury to the wound, apthya sevana by vraṇita and improper wound dressing there is Vitiation of Vāta and Rakta, followed by accumulation and drying up of vitiated Rakta in the site of the wound leading to the formation of an elevated structure associated with burning sensation and itching. This hard structure formed is called as Vraṇa Granthi.[1] The pathogenesis of Vrana granthi is similar to that of Keloid. Keloidal scarring is one of the most frustrating clinical problems in wound healing. Keloids form following dermal injury and exhibit exuberant, indefinite growth of collagen.[2,3] Keloid management can be difficult and frustrating, and the mechanisms underlying keloid formation are only partially understood. Despite the growing literature investigating reliable methods for keloid management, no standardized guidelines or treatment protocols are supported by academic governing bodies. Using original and current literature of Vranagranthi and keloid, this comprehensive review presents the major concepts of Vranagranthi [keloid] pathogenesis and their treatment options.

Keywords: Vranagranthi, Keloid, Hypertrophic scar.