Abstract

A COMPARATIVE STUDY ON THE EFFECT OF HERBAL EXTRACTS AND ANTIBIOTICS ON ENTERIC PATHOGENS

Bansode D.S.* and Chavan M.D.

Abstract

In the present study antimicrobial activity of crude Curry (Murraya Koenigi) leaves extract observed in comparison with Standard antibiotics Cholistin, Erythromycein, Ciprofloxin, Methicillin, Ampicillin and Cephalosporin. In this study, the antimicrobial efficacy of crude Curry leaves extract was examined and tested against following bacterial cultures those were Salmonella typhi (4 strains), Shigella dysenteriae (7 strains), Shigella flexinary (6 strains), E.coli (4 strains), Enterobactor spp. (4 strains) and Salmonella paratyphi B (7 strains). Antimicrobial analysis was done by using agar well diffusion method against selected enteric pathogens. Curry leaves extract showed highest antimicrobial activity against Salmonella typhi strain I (ZOI- 16mm), Shigella dysenteriae strain VI (ZOI- 19mm), Shigella flexinary strain I (ZOI- 16mm), E.coli strain III (ZOI- 18mm), Enterobactor spp. strain IV (ZOI- 20mm) and Salmonella paratyphi B strain IV (ZOI- 19mm). Salmonella typhi strain IV showed no ZOI with Curry leaves extract but this strain was observed sensitive to antibiotic Ciprofloxin (ZOI- 15mm). Shigella flexinary strain III showed no ZOI with Curry leaves extract but this strain was observed sensitive to antibiotic Ampicillin (ZOI- 11mm). The results suggested that the crude Curry leaves extract has significant antibacterial activity against tested microorganisms as compared to standard antibiotics. The results of this study showed that some pathogenic enteric bacteria were observed resistant to standard antibiotics but they were sensitive to the studied crude Curry leaves extract. The results of the present study also support the medicinal usage of the Curry leaves.

Keywords: Curry (Murraya koenigi), Antimicrobial activity, Enteric pathogens, Standard antibiotics etc.