Abstract

A REVIEW ARTICLE ON ORAL PHARMACEUTICAL DOSAGE FORMS AT DIFFERENT STATES

Sutha P.*, Sharma M. S., Sreethilak N. K., Sibiraj S., Sangameswaran B., Nithyapriya K.

.

Abstract

Oral Liquid Dosage Forms in Pharmaceuticals include Syrup, Oral Suspension, Oral Solution, Oral Drop, Oral Emulsion, Mixture, Linctuse, and Elixir. Oral liquids are homogeneous liquid preparations, usually containing a solution, an emulsion, or a suspension of one or more active ingredients in a suitable liquid base. They are prepared for oral administration either as such or after dilution. They may contain other substances such as suitable dispersing, solubilizing, wetting, emulsifying, stabilizing, suspending, thickening agents and antimicrobial substances for preservation. When creating pharmaceutical dosage forms, the selection of excipients plays a significant role in the formulation and formulation research. Excipients physical, mechanical, and chemical characteristics have a big impact on the final product and other formulation parameters like disintegration, dissolution, and shelf life. As a result, numerous studies have been carried out to assess how drug-excipient interactions affect the formulation as a whole. The information on the excipient’s physical and chemical instability and compatibility with the active pharmaceutical component in solid oral dosage forms during various drug manufacturing procedures is reviewed in this article. The impact of these interactions on the drug formulation process has been discussed in detail. Examples of multiple excipients used in solid oral dosage forms have been included to elaborate on drug-excipient interactions.[1]

Keywords: Oral Solid Dosage Forms, Powder, Capsules, Tablet, Pills, Excipients for Solid Dosage Form.