Abstract

LITERARY REVIEW OF YAKRITDALYODARA W.S.R. TO FATTY LIVER AND ITS AYURVEDIC MANAGEMENT

Mamta Sirvi* and Ravi Sharma

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Abstract

Fatty liver disease, encompassing both alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD), has emerged as a significant public health concern globally. NAFLD, characterized by the accumulation of lipids in hepatocytes in individuals with minimal or no alcohol consumption, is associated with obesity, insulin resistance, and metabolic syndrome. This condition can progress to non-alcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma (HCC).[1] There are various symptoms such as confusion, fatigue, weakness etc. Fatty liver disease's main lifestyle factor is overeating. Alcohol intake causes alcoholic fatty liver disease. Ajirna (indigestion), Sthaulya (obesity) and Prameha (diabetes mellitus), which is caused by Annavaha's vitiation. Rasavaha and Medovaha Srotas acts as Nidanarthakara Rogas (diseases that cause other diseases), which may cause non-alcoholic fatty liver disease. Recent studies indicate that the global prevalence of NAFLD is increasing, affecting approximately 25% of the population, with variations across different regions.[2] The pathogenesis of fatty liver disease involves complex interactions between genetic, environmental, and metabolic factors. Insulin resistance plays a crucial role in the development of hepatic steatosis, while oxidative stress and inflammation contribute to the progression from simple steatosis to NASH. Management strategies for fatty liver disease primarily focus on lifestyle modifications, including diet and exercise, and pharmacological interventions in more advanced cases.[3] Ayurvedic literature states that Panchakarma (Virechana) and herbs like Bhumiamalaki, Guduchi and Rohitaka etc. protect the liver and improve its functioning.)

Keywords: Fatty liver, Sthaulya, Prameha Roga, Yakritdalyodara.