Abstract

A REVIEW: RECENT ADVANCEMENTS IN ORAL DISPERSIBLE FILMS

Vaibhav Bhatt*, Chainesh Shah and Umesh Upadhyay

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Abstract

Oral Dispersible Films (ODFs) represent a significant advancement in drug delivery, offering a patient-friendly alternative to traditional dosage forms. This review explores the various aspects of ODFs, including their composition, manufacturing techniques, applications, and challenges. Key components such as film-forming polymers, plasticizers, and taste-masking agents are discussed, along with the methods used for ODF production, including solvent casting, hot melt extrusion, and 3D printing. The review also highlights the therapeutic benefits of ODFs, particularly for pediatric, geriatric, and veterinary patients, while addressing the limitations related to stability, scale-up, and regulatory compliance. Furthermore, emerging trends such as personalized medicine, biologics delivery, and smart ODFs are examined, underscoring the potential of ODFs in future pharmaceutical applications. This comprehensive review provides insights into the current state and future prospects of ODFs, emphasizing their role in enhancing patient compliance and therapeutic efficacy.

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