Abstract

EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF ETHANOLIC EXTRACT OF AEGLE MARMELOS ON HEPATOTOXICITY INDUCED RATS

Mrs Putta Swetha*, Dr. K. Hemamalini, Poojitha K., Hafeezunnisa, Divyasri Ch., Sunitha R. and Geethanjali N.

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Abstract

Herbal drugs are traditionally used in various parts of the world to cure different diseases. The Ayurveda and Siddha medical systems are very famous medical practices in Indian traditional medicines. In the present research studies, Bael leaves (Aegle marmelos, family of Rutaceae) which are also called as Bilva in ancient Sanskrit was used as herbal drug and its hepatoprotective effect in INH induced liver injury in albino rat was evaluated using essential biochemical parameters. The experiments were performed with four groups of animals. The experimental animals were administered with EEAM was fed to animals for next 21 days. The results were compared with the standard herbal drug silymarin (133.04 g/g tissue). The experimental results indicate that, the Bael leaves have excellent hepatoprotective effect. A similar experimental result was also observed in other biochemical parameters.

Keywords: Isoniazid, Aegle marmelos, Hepatoprotective activity, Marker enzymes.