Abstract

TERATOGENICITY: A BASICS REVIEW

Disha V. Kale*, Prof. Babasaheb L. Chopade and Dr. Megha T. Salve

Abstract

Teratogens are environmental agents that can cause birth defects or abnormalities in a developing fetus when a pregnant mother is exposed to them. These agents can be physical substances or conditions affecting the mother, resulting in physical or functional defects in the embryo. Exposure to teratogens during pregnancy can significantly impact fetal development, with approximately 4-5% of birth defects attributed to teratogen exposure. The critical period of susceptibility is believed to be between 10-14 days after conception, when the blood supply connection forms between the fetus and the pregnant individual. Since the term “Teratogens” was first coined in Paris in 1932, research has highlighted the importance of identifying and mitigating teratogen exposure to ensure healthy fetal development. This knowledge is crucial for expectant mothers, healthcare providers, and policymakers seeking to prevent birth defects and promote optimal prenatal care.

Keywords: teratogen, FDA, term teratogen, Pregnant person, etc.