Abstract

TO STUDY THE DRUG UTILIZATION EVALUATION OF ANTIBIOTICS IN LOWER RESPIRATORY TRACT INFECTION IN TERITARY CARE TEACHING HOSPITAL

Dr. Santhosh Uttangi*, Prof. J. S. Venkatesh, Acsah Ann Reji, Aji Antony, Anjana S. S. and Ansu Abraham

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Abstract

Most people will develop lower respiratory tract infection every year. LRTI tends to be more dangerous than URTI. Management of LRTI were preferred with antibiotics as there is an increasing incidence of antimicrobial resistance it is necessary to conduct drug utilization studies. Aim of this study was to identify and evaluate the antibiotics utilized in patient with lower respiratory tract infections at tertiary care teaching hospital. A total of 183 patients with LRTI (18 to above 65years) in government Chigateri District Hospital Davengere (tertiary care teaching hospital) were taken, the data was collected from the case sheets of patients and recorded in a data collection form. The collected data were analyzed in MS Excel and descriptive statistics were used for analyzing the result of the study. Among all antibiotics ceftriaxone were found to be 159(51%) followed by azithromycin 92(29.6%), piperacillin + tazobactum 39(12.58%), doxycycline 7(2.25%), ciprofloxacin 1(0.32%), ofloxacin 2(0.64%), meropenem2(0.64%), clindamycin2(0.64%. Whereas cefoperazone + salbactum, amoxicillin + claculanate, amikacin, cefpodoxime, ceftriaxone + salbactum and streptomycin were prescribed in limited cases. The present study was conducted to analyse rational prescribing of antibiotics in patients with LRTI and an overall pattern of antibiotics usage. Area of concern in the present study is polypharmacy and use of antibiotics in LRTI without following any guideline. From our study we conclude that drug utilization studies have the potential to make objective evaluation of irrationality and empiric antibiotic prescription.

Keywords: Lower respiratory tract infection (LRTI), Drug utilization evaluation (DUE), Antibiotics, Inpatients, Rational use.