Abstract

REVIEW ON OVERVIEW OF NASOPULMONARY DRUG DELIVERY SYSTEM

*Khandagale Ravindra, Zagade Sumit, Panhalkar Narayan, Kulkarni Onkar, Choudhari Pruthviraj and Mr. Vaibhav Bodkhe

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Abstract

Exploring the possible future uses of nasopulmonary drug delivery devices for nasal drug administration is the goal of this comprehensive analysis. Nasal delivery of medication has received a lot of attention because of its many advantages, including as rapid absorption, avoiding first-pass metabolism, and non-invasive administration. This article provides an overview of nasal structure and physiology and discusses the factors influencing medication absorption and bioavailability. It also discusses the advantages and disadvantages of the different nasopulmonary drug delivery techniques, such as gels, powders, and sprays. The problems of nasal medication delivery, including issues with mucociliary clearance, nasal irritation, and formulation, are also covered in the paper. Additionally, the potential application of nasopulmonary medication delivery systems to treat a number of diseases, such as allergies, respiratory conditions, and systemic obstacles is discussed. As the review concludes with a prediction for their future, additional research and development are needed to optimize the efficacy and safety of nasopulmonary medication delivery systems.

Keywords: nasal pulmonary; nasal spray; nasal mucosa; gels; drops; nasal approaches; nasal route; nasal delivery.