Abstract

A PROSPECTIVE STUDY ON PRESCRIPTION PATTERN OF ANTIDIABETIC DRUGS IN TYPE2 DIABETES MELLITUS PATIENTS WITH OR WITHOUT COMORBIDITY IN TERTIARY CARE TEACHING HOSPITAL

Prof. J. S. Venkatesh*, Amritha Balu, Sherin Elza Raju, Sneha Mini Mathew Roy

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Abstract

TYPE 2 DM is a increasing at an alarming rate and has been noticed as one of the leading cause of death and disabilities world wide. Hence this study focused on prescription pattern, quality of life and other comorbidities. To study the pattern and uses of major anti-diabetic class of given for diabetes and comorbities, the current use of Antidiabetic and their rational use and to assess QOL in Type 2DM. A prospective observational study was carried out for a period of six months in inpatient medicine department of Chigateri district hospital, Davangere (Tertiary care teaching hospital) 157 case reports of patient with type 2 DM were reviewed, the details such as demographics, specified drug prescribed, QOL were recorded. Out of 157 patients, majority of patients diagnosed with type 2 DM were male (64%) the distribution of disease was higher in age group between 45-54 years, HbA1c range in between >7.65% and GRBS range in between 220-300 mg/dl, duration of type 2 DM was more in 1-5years(45.4%), HTN was most observed comorbid condition. Majority of patients received metformin as mono therapy (33.51%), and also combination therapy of various antidiabetic drugs were prescribed. Average number of anti-diabetic drugs prescribed per prescription was 3, drugs prescribed by generic name accounted for 137 and drugs from essential drug list was 148. The study showed that metformin was predominantly prescribed oral anti-diabetic drug both as mono therapy and combination therapy. HTN was commonly found co-existing condition. Prescribing drug by brand names were high and from essential drug list were low. Number of drugs prescribed per prescription was decreased which is a welcome sign and need to be encouraged. The information leaflet has significant impact on patients with diabetes and other comorbidities towards the diseases management showing the usefulness of PILS.

Keywords: Type 2 Diabetic mellitus, Hypertension, Quality of life, Glycosylated Haemoglobin, General Random Blood Sugar, Patient Information Leaflet.