Abstract

ANTIMICROBIAL ACTIVITY OF CINNAMOMUM CAMPHORA LEAVES EXTRACT AGAINST HUMAN PATHOGENIC BACTERIA

Md. Mahamudul Hasan Bhuiyan, Kamrun Nahar Paulin, Md. Awlad Hossain Babu, Ayrin Akther Mili, Md. Wasif Iqbal and Md. Abdul Mannan*

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Abstract

A medicinal plant is a plant that has therapeutic properties and is used for the prevention, treatment, or alleviation of diseases or health conditions. These plants contain bioactive compounds that can provide health benefits, whether consumed, applied topically, or used in traditional remedies. Medicinal plants have been integral to various traditional healing systems and are increasingly studied for their potential in modern medicine. Microbial diseases occur when harmful organisms such as bacteria, viruses, fungi or parasites enter and multiply in the body. These diseases can affect many parts of the body and cause a variety of symptoms depending on the type of disease and the location of the disease. Most people in developing countries get their basic health care from plants or organic preparations. Many plants have been found to have antibacterial properties. Cinnamomum camphora, commonly known as the camphor tree, is known for its antibacterial properties, primarily due to the presence of camphor and other active ingredients in its volatile oil. Cinnamomum camphora leaf extract has antibacterial properties. Methanolic extracts of Cinnamomum camphora leaves suppressed the growth of harmful microorganisms i.e., Escherichia coli, Staphylococcus aureus, and Streptococcus pyogenes. The result of this study revealed that the test disk containing 250μg, 500μg and 1000μg Cinnamomum camphora leaf extract showed 10 mm, 13 mm and 15 mm zones of inhibition against Escherichia coli; 8 mm, 11 mm and 13 mm zones of inhibition against Staphylococcus aureus; and 6 mm, 8 mm and 10 mm zones of inhibition against Streptococcus pyogenes. On the other hand, positive control 30 μg Amikacin containing standard antibiotic disk showed 14 mm, 12 mm and 10 mm zone of inhibition against Escherichia coli, Staphylococcus aureus, and Streptococcus pyogenes. This research concluded that Cinnamomum camphora leaf extract contains antimicrobial properties. The composition of Cinnamomum camphora leaves extract as a natural source for antibacterial medication development might be clarified by a thorough and comprehensive investigation.

Keywords: Antimicrobial activity, Zone of inhibition, Cinnamomum camphora.