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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

OTOSCLEROSIS: A PROGRESSIVE BONE REMODELING DISEASE AFFECTING THE MIDDLE EAR

Rutuja R. Gaikwad*, Pratik B. Bhange and Megha T. Salve

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Abstract

Otosclerosis is a localized, progressive bone remodeling disease that primarily affects the stapes bone in the middle ear, leading to conductive hearing loss. The disease is characterized by abnormal bone growth around the stapes plate, resulting in its fixation and impeding sound conduction to the inner ear. The etiology of otosclerosis remains unknown, but it is inherited and follows a specific pattern. The disease can also involve the inner ear, specifically the cochlea, and can occur independently or simultaneously at the base of the stapes and/or the cochlear capsule. This abstract provides an overview of the anatomy of the human ear and the pathophysiology of otosclerosis, highlighting its impact on hearing and the need for further research into its causes and treatment.

Keywords: Otosclerosis, None Remolding, Cochlea, Autosomal, Sensorineural, Protease, Tinnitus, arches, Restorative phase, Disposition.


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