Abstract

MODIFICATION OF ANJHADADI TAILA INTO MALAHARA FORM AND ITS GAS CHROMATOGRAPHY-MASS SPECTROMETRY (GCMS) ANALYSIS

Dr. Shriya S. Revankar* and Dr. Nayana S. Pai

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Abstract

Bhaishajya Kalpana – ‘Ayurvedic pharmaceutics’ a branch mainly focuses on classical preparations, product design, formulation development with the innovative approach. Among all the classical preparations, Sneha preparations occupy major role either as external applications or internal medications. The word ‘Malahara’ refers to semisolid preparations acting chiefly as local anodynes and sedatives for local application for various lesions, containing active drugs mixed with oil, ghee, beeswax, petroleum jelly etc. Anjhadadi Taila is an classical formulation mentioned in Sahasrayogam mainly indicated in Ostarogas, containing five drugs namely Bhumyamalaki (Phyllanthus amarus Webst.), Nirgundi (Vitex negundo Linn.), Nimba (Azadirachta indica A.Juss.), Haridra (Curcuma longa Linn.), Tila Taila (Sesamum indicum Linn.), which are known for their antioxidant, antiinflammatory, anti-microbial, anti-cancer and wound healing properties. Most common symptoms of Osta Rogas includes cracking of lips, pain, discomfort, soreness, inflammation, tenderness, burning sensation leading to severely bleed and infected if not treated. Malahara has Snehana (oleation), Ropana (healing), Lekhana (Scrapping) and Varnya (beautifying) property, depending on the combination of active ingredients present in the formulation. In the present study Anjhadadi Taila was modified into Malahara, for making the product user friendly and to develop preliminary standards of the formulation, prepared Anjhadadi Malahara was analysed for instrumental analysis Gas chromatography and mass spectroscopy including various other physico-chemical analysis like organoleptic characters, uniformity of content, loss of drying at 105℃, spreadability and microbial contamination.

Keywords: Anjhadadi Taila, Anjhadadi Malahara, Ostarogas, Lips, Gas chromatography and mass spectrometry GC-MS, Physico-chemical analysis.