Abstract

FORMULATION AND EVALUATION OF FAST MOUTH DISSOLVING TABLETS OF FLUPIRITIN BY USING CASSAVA STARCH AS BINDING AGENT

S.Mounika Reddy*, K. Pooja sritanya, B.Mallesh, V. Sai Kumar, L.Krishnam Raju, Ch.Srinivas Reddy and R.Suthakaran.

Abstract

Flupiritin is an amino pyridine that functions as a centrally acting analgesic and anti-inflammatory. Flupiritin mainly using in Polycare therapy. It first became available in Europe in 1984. Flupiritin is sold by Intas Pharma under the brand name Pruf in India. Like Nefopam it is unique among analgesics in that it is a non-opioid, nonsteroidal centrally acting analgesic. Flupiritin is formulated using direct compression technique. In 2010 the chemically related drug Retigabine was approved by the FDA as an anticonvulsant for the treatment of refractory partial-onset seizures in treatment-experienced patients. Flupiritin is used as an analgesic for acute and chronic pain, in moderate-to-severe cases. Its muscle relaxant properties make it popular for back pain and other orthopedic uses, but it is also used for migraines, in oncology, post-operative care, and gynecology. Flupiritin has been noted for its neuroprotective properties. It is used in the treatment of long chronic disorders.

Keywords: Poly care therapy, analgesic, anti-inflammatory, neuroprotective, Retigabine and Nefopam.