Abstract

A REVIEW ON PELLETS AND PELLETIZATION TECHNIQUES

Ankit Sharma*, Ajay Kaundal, Ritesh Kumar, Ansh Nag, Kumari Shakshi, Siya and Anshul

Abstract

Oral Multiarticulate system (OMS) has more therapeutic applications when compared to unit solid dosage forms. Multiarticulate are discrete units which constitute multiple unit systems. The drug can be enhanced for prolonged period of time by manufacturing OMS into extruded spherical particles. Alot of research studies are being done on multiarticulate system as drug delivery systems. With the advancement of technology, various techniques have been developed for the preparation of pelletsas it seems to be good way for administration of many drugs. The more focus is on operational Procedures, preparative areas and physical properties of particles which have greater effect on the efficacy of the developed system. The present review mainly discusses advancements in the manufacturing techniques for pellets pertaining to their oral delivery. In addition, conversion of pellets into suitable dosage from for oral delivery and evaluation thereof has also beendiscussed here.

Keywords: Multiarticulate system, pelletization, extrusion spheronization.