Abstract

A BRIEF OVERVIEW ON 3D PRINTING OF MEDICINES

Abhishek Digambar Pawar*, Rohan Dilip Murdare, Gaurav Dattatray Shirsath, Mayur Shaneshwar Jadhav, Pavan Dattatray Rashinkar and Tejas Santosh Gondhavne

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Abstract

There are applications for printing in a variety of industries, including electronics, aviation, and medical. The pharmaceutical business might benefit greatly from 3D printing's highly customizable and individualized features. The potential applications of 3D printing in the pharmaceutical industry piqued our curiosity. We discovered that the following medical uses for 3D printing technology exist: Thirdly, it can precisely control the distribution of cells, extracellular matrix, and biomaterials to build organs or organ-on-a-chip for drug testing; secondly, it can print tablets with specific shape and structure to control the release rate; and thirdly, it can print pills on demand based on the patient's condition, making the dosage more appropriate for each patient's unique physical condition; Lastly, technology might be utilized to create transdermal microneedle patches to lessen patient pain or print loose porous pills to help with swallowing issues. The purpose of this study was to determine whether fused deposition modeling (FDM) and 3D printing might be used to create cinnarizine tablets. Cinnarizine, an antihistamine medication, was effectively loaded into commercial polyvinyl alcohol (PVA) and was used as a model drug for investigation. AutoCAD was used to create the tablet, and Cura Ultimaker 4.4 was used to cut the design. After printing the filaments into hollow, structural tablets with no infill, the medicine cinnarizine was added, and the upper surface was sealed using 3D printing.

Keywords: Additive manufacturing, FDM, fast prototyping, tablets, oral dose forms, 3D printing.