Abstract

DESIGN, FORMULATION IN-VITRO EVALUATION OF HERBAL MICROSPONGE BY USING “RICINUS COMMUNIS” LEAF EXTRACT

ChoppadandiMounika*, G. Naresh, Abhishek Chawan, Rama Krishna Prasanna, Raju Manda and R.Suthakaran

Abstract

The present study was carried out to formulate “Herbal Microsponges” by using “Methanolic” and “Petroleum ether” extracts of “Ricinuscommunis” leaves, to explore the drug release based on the type and concentration of “Polymers” used in the formulation. Formulation was made by methanolic and petroleum ether extracts of Ricinuscommunisand made into gel form. The extract was subjected to preliminary phytochemical screening which indicates the presence of flavanoids, tannins and terpenoids. Isolation of flavonoids was done which consists anti inflammatory activity and by using flavonoids Microsponges were prepared and the evaluation studies of each formulations were compared.

Keywords: Herbal Microsponges, Methanolic extract, Petroleum ether extracts, Ricinuscommunis, flavanoids, Polymers, anti inflammatory activity.