Abstract

NOVEL DRUG DELIVERY SYSTEM IN HERBAL’S

*Ayesha A. Shaikh, Prof. Aaditee A. Gore and Dr. Mehga Salve

Abstract

Because of their natural origins, less side effects, and therapeutic benefits, the use of herbal medications has increased significantly. However, issues including instability, low bioavailability, and the requirement for exact dosage frequently restrict their effectiveness. By improving the transport, absorption, and therapeutic efficacy of herbal components, novel drug delivery systems (NDDS) provide creative answers to these problems. Methods that enhance the stability, bioavailability, and targeted distribution of herbal actives include solid lipid nanoparticles (SLNs), systems. For example, solid lipid nanoparticles (SLNs) offer a stable and controlled delivery method that protects the active compounds from degradation; the use of biopolymers in the creation of delivery matrices aligns with the natural essence of herbal medicines, making them biocompatible and safe for long-term use; liposomes and phytosomes improve the solubility and stability of hydrophobic herbal extracts, which in turn enhances their cellular uptake; and nanotechnology-based delivery systems for controlled release and site-specific targeting, minimizing toxicity and optimizing therapeutic action.

Keywords: Herbal drug; novel drug delivery system; natural products, solid lipid nanoparticles (SLNs), liposomes, phytosomes.