Abstract

REVIEW ON: FORMULATION AND EVALUATION OF SUBLINGUAL FILM

Sejal Rohidas Kanade*, Snehal Santosh Pendbhaje, Sakshi Sanjay Dighe, Akanksha Bhagwan Ghadge

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Abstract

Fast-dissolving orally disintegrating films are formulated to dissolve quickly when they come into contact with wet surfaces or fluids, such as saliva, typically within seconds. Unlike tablets, capsules, or oral liquids, they do not require additional liquids like water, making them a highly convenient dosage form for patients. This formulation also offers significant marketing benefits. Orally disintegrating films are particularly advantageous for pediatric and geriatric patients, as well as those with a fear of choking, due to their ease of administration and popularity. Since the drug is absorbed directly into the bloodstream through the mucosal membrane in the mouth, it bypasses degradation in the gastrointestinal tract and avoids first-pass metabolism. This enhances the drug's availability in plasma, thereby improving its therapeutic efficacy.

Keywords: This formulation also offers significant marketing benefits.