Abstract

CHARAGE TRANSFER COMPLEXE OF LOSARTAN K WITH DDQ

Dr. T. Charan Singh*

Abstract

Molecular complex of 2,3- Dichloro 5,6-dicyano –para- benzoquinone (DDQ) with some antibiotic drugs have been studied spectrophotometrically in chloroform. All the complex exhibited charge transfer bands (s) in the visible region where neither donor acceptor have any absorption. The stoichiometry of the each of the complex is found to be 1:1 and is unaffected by variation of temperature. The complex are inferred to be π-π* type. The ioniza-tion potential of the donors has been evaluated from the energies of CT bands. The stabilities and thermodynamics parameters of the complex have been determined from the absorption studies on the CT bands. The variation of position of CT bands and the stabilities of the complex have been correlated with the structures of the drugs.

Keywords: DDQ, CT complex, Losartan K,, Chloroform, Stability constant.