Abstract

EVALUATION OF NEUROPROTECTIVE ACTIVITY OF MEDICINAL PLANT EXTRACT

Vishal Thakur*, Sarvesh Maurya and Rachana Sarawade

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Abstract

Neuroprotection aims to protect neurons or slow disease progression and secondary injuries by faltering or at least slowing the loss of neurons Despite differences in symptoms or injuries associated with CNS disorders. The term Neurodegeneration is a combination of two words- “neuro” stand for nerve cells and “degeneration” stand for progressive damage. Thus, in the strict sense of the word, neurodegeneration corresponding to any pathological condition primarily affecting neurons. Among the many of different neurodegeneration disorder, so far, including Alzheimer disease (AD), Parkinson disease (PD), Huntington disease (HD), and Amyotrophic lateral sclerosis (ALS). In practice, neurodegeneration disease represents a large group of neurological disorder with pathological expression and heterogenous clinical affecting specific subset of neurons.

Keywords: Parkinson disease (PD), Amyotrophic lateral sclerosis, Central Nervous System, Catechol Omethyl transferase, Catechol Omethyl transferase.