Abstract

ROLE OF SEVERAL BIOACTIVE COMPOUNDS IN DIABETES MELLITUS MANAGEMENT

Wesam M. Hussein*

Abstract

With a rising incidence, diabetes mellitus (DM) is one of the most significant global health issues. This review demonstrates the function of four bioactive compounds (Thymoquinone, gallic acid, Oleuropein, and quercetin) in the treatment of diabetes mellitus. Thymoquinone appears to be a promising natural compound for managing diabetes, with effects on blood glucose levels, oxidative stress, and inflammation. Its multifaceted actions suggest that it could be a valuable adjunct to conventional diabetes therapies. Gallic acid affects oxidative stress, inflammation, lipid profiles, and blood glucose control, making it a potentially useful drug for treating diabetes. It may be a useful supplement to traditional diabetic therapies, based on its diverse activities. Oleuropein seems to be a potential natural substance for diabetic treatment with effects on blood glucose regulation, insulin sensitivity, and protection against oxidative stress and inflammation. Its diverse range of impact raises the possibility that it might be a useful supplement to traditional diabetic treatments. Quercetin appears to be a possible natural remedy for diabetes with beneficial effects on blood glucose regulation, insulin sensitivity, oxidative stress, and inflammation. Its varied effects imply that it could be a useful supplement to diabetic treatments.

Keywords: Diabetes; Thymoquinone; Gallic acid; Oleuropein; Quercetin.