Abstract

REVIEW OF PHYTOCHEMISTRY AND PHARMACOLOGY OF HOPEA PARVIFLORA

S. Shervin Jose* and V. Jenila Jose Jancy and J. John Wesley

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Abstract

The Hopea parviflora tree, which belongs to the Dipterocarpaceae family, is endemic to the tropical evergreen forests of southwestern India, particularly those surrounding the Western Ghats in Karnataka. Extracts from H. parviflora leaves have strong antidiabetic and antioxidant properties. Hopea parviflora stem bark exhibits antiinflammatory properties. Ellagic acid-3,3',4-trimethoxy-4'-O-a-Lrhamnopyranoside decreased the activity of pro-inflammatory mediators like NO, TNF-a, IL-6, 5-LOX, and COX-2 and enhanced the activity of the anti-inflammatory mediator IL-10 via blocking the NFkB pathway. Ethanol, methanol, and water extracts of Hopea parviflora beddome sawdust were the most effective against Staphylococcus areus.

Keywords: Hopea parviflora, Dipterocarpaceae, Anti-oxidant, Anti-diabetics, Anti-inflammatory, Anti-bacterial.