Abstract

GC-MS ANALYSIS, PHYTOCHEMICAL PROFILE, AND ANTIBACTERIAL EFFICACY OF THE MEDICINAL PLANT PLUMBAGO ARABICA

Haribhau R. Aher, *Subhash L. Kakad and Suprita Rana

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Abstract

The present study focused on determining the phytochemical composition of the ethanol root extract of Plumbago arabica through GC-MS analysis and characterization. The desiccated root were pulverized and immersed in various solvents of ascending polarity: chloroform, methanol, ethanol, and water. The phytochemical constituents in the methanolic extracts were identified using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. The spectra of unknown compounds were analysed in comparison to known substances using the National Institutes of Standards and Technology database. The substances were considered to possess significant pharmacological and biological relevance. The extracts shown significant antibacterial activity when evaluated against the development of specific bacteria and fungi. The substances were considered to have significant pharmacological and physiological relevance. This study highlights the plant's significance as a phytopharmaceutical resource by demonstrating that it includes a number of bioactive chemicals.

Keywords: Plumbago arabica, Phytochemicals, GC-MS, Antimicrobial.