Abstract

INVESTIGATION ON IN VITRO ANTI-OXIDANT AND ANTIINFLAMMATORY ACTIVITY BIO-SYNTHESIS OF NANO PARTICLE ETHANOLIC EXTRACT (CARDIOSPERMUM HALICACABUM)

T. Pradeepa*, G. Dinesh, T. Harish, S. Krithik Roshan, V. Poongavanam, E. Saravanakumar and P. Yuvan Shankar

Abstract

Cardiosperum halicacabum is Versatile Medicinal Plant used in Indian system of medicine. Silver nanoparticles (AgNPs) were synthesized from the ethanolic extract of Cardiosperum halicacabum by an eco-friendly method and explored for possible pharmacological action. Biosynthesised nanoparticles were investigated for in vitro antioxidant activity by DPPH assay using ascorbic acid as a standard and also tested for in vitro antiinflammatory activity by protein denaturation assay using diclofenac as a standard for the assessment of anti-inflammatory potential. Biosynthesis Nanoparticles Cardiosperum halicacabum Formation Verified by Color Changes from Colorless to Reddish Brown in Color and Surface Plasmom Resonance at 400-450 nm [465 nm 0.658 Absorption] from the Studies AgNPs has (70%) Significant Anti-Oxidant and no Anti-Inflammatory Activity.

Keywords: Cardiosperum halicacabum, antioxidant, DPPH assay, anti-inflammatory, Sliver nanoparticle AgNps, UV.