Abstract

A REVIEW ON NANOPARTICLES: INTRODUCTION, CLASSIFICATION, SYNTHESIS AND APPLICATIONS

Juvvanapudi Asiel*, Mohammad Fiza Suhana, Dasari Vijayamani, Kota Pallavi Krishna and Athmakuri Navyasri

Abstract

The pharmacokinetic and pharmacodynamic characteristics of several kinds of pharmacological molecules have recently been changed and improved by the physical usage of particulate systems, such as nanoparticles. In vivo, they have been utilized to protect the drug entity in the systemic circulation, limit the drug's access to certain areas, and transport the drug to the site of action at a steady and regulated rate. It is evident that drug delivery research is shifting from the micro to the nanoscale. Thus, nanotechnology is becoming a medical discipline that is anticipated to yield substantial therapeutic advantages. One of the hardest jobs for pharmaceutical formulation researchers is creating efficient nanodelivery systems that can deliver a medication precisely and securely to the intended site of action. To sustain promising scientific results and therapeutic advancements, they are working to restructure and add additional indications to the current blockbuster medications. The primary nanodelivery technologies include liposomes, lipid or polymeric nanoparticles, and nanoemulsions. Particulate vesicle systems have been used as drug carriers for both small and large molecules in a significant amount of research conducted in recent years on the basis of novel drug delivery methods. Drugs' medicinal efficacy and adverse effects have been enhanced using nanoparticles. In general, a variety of processes have been used to create nanoparticles, including ionic gelation or coacervation of hydrophilic polymers, polymerization of monomers, and dispersion of preformed polymers.

Keywords: Nanoparticles, Nanotechnology, Nano drug delivery, Targeted drug delivery.