Abstract

ROLE OF HERBAL NANOPARTICLES IN TREATMENT OF INFLAMMATION

Pratiksha Mishra*, Himanshu Pal and Vikash Chandra Sharma

.

Abstract

Inflammation is a response to an injurious stimulus, which is caused by a wide variety of noxious agents involving four basic principles i.e. calor, dolar, rubor and tumor. A distinctive feature of inflammatory response in relation to other facts of anti parasite defense is that damage to the self is unavoidable. Several synthetic pharmaceutical products in various dosages form are available in the market for Inflammation treatment but are less preferred because of their elevated allergic reactions, repeated therapy, and side effects. Herbal products provide relief with comparatively less side effects. Now a day, for effective treatment, more and more search is diverted towards herbals. Although a number of herbal products are available for topical admistration like creams, ointment, gel etc, and these conventional formulations have less effect to the body and have little percutaneous absorption. In this respect, the newer approaches like silver nano formulations are developed as these formulations are stable and with high drug loading capacity and increased percutaneous absorption. Alcoholic extract of peel of Citrus lemon were screened for the presence of phytochemical constituents. Silver nanogel of Citrus lemon and peel extract can overcome the problems related with conventional formulations such as low uptake, poor penetration and high cost.

Keywords: Silver nano particles, Inflammation, Citrus lemon, Herbal products, polymer, Phytochemical Screening.