Abstract

OVERVIEW ON: ISOLATION, ANALYSIS PROCESS, AND PHARMACOLOGICAL ACTIVITY OF GALLIC ACID

Priya Gandhi*

Abstract

Gallic acid (3, 4, 5-trihydroxybenzoic acid) is a phenolic acid compound. Nearly every component of the plant, including the bark, wood, leaf, fruit, root, and seed contains a significant amount of Gallic acid and its derivatives. Isolation of Gallic Acid from fresh or dried plant material by using different techniques like Soxhlet method, reflux, Column Chromatography, Matrix solid phase extraction, maceration, and Sonication etc. Based on in vitro studies Gallic acid has pharmacological activities, including as an antioxidant, antiinflammatory, antineoplastic, gastrointestinal, neuropsychological, metabolic disease, and cardiovascular disorders. This article provides details on the isolation process, analysis, and pharmacological effect of Gallic acid. Gallic acid identification can be done using Thin Layer Chromatography (TLC), High-Performance Liquid Chromatography (HPLC), and High Performance Thin Layer Chromatography (HPTLC).

Keywords: Gallic Acid, sources, isolation methods, physico-Chemical Properties, therapeutic effects, HPLC, HPTLC.