Abstract

PHARMACEUTICO-ANALYTICAL STUDY OF KODASHARI GUTIKA

Syeda Almas*, Radhika Ranjan Geethesh P., Ashok Kumar B. N., Sushmitha V. S., Ravindra Angadi

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Abstract

Kodashari Gutika, a classical Ayurvedic Herbo-mineral formulation mentioned in Sahasrayogam containing ingredients such as Shuddha Hingula, Shuddha Vatsanabha, and Pippali, has been indicated in various types of Jwara namely Taruna Jwara, Taapa Jwara, and Sannipataja Jwara. Most of the signs and symptoms of Sannipataja Jwara closely resemble those of Typhoid Fever. The research aims to evaluate the pharmaceutical and analytical aspects of this formulation, considering its potential application in Typhoid fever. Aims and Objectives: this study aims to evaluate the pharmaceutical, analytical properties of Kodashari Gutika. Methodology: The present study has been carried out in two stages namely, pharmaceutical, analytical. In the pharmaceutical study, Shodhana of ingredients of Kodashari Gutika was carried out as per the classical textbooks. The preparation of Kodashari Gutika was carried out according to the reference of Sahasrayogam. In the analytical study, the sample of Kodashari Gutika was subjected to a series of analytical tests to establish quality parameters. Results: The pharmaceutical study at various steps of Shodhana and Vati Nirmana complied with the standard operating procedures mentioned in the classics and provided descriptive data for the methods adopted. The analytical study provided standardization data for the formulation, including its physicochemical properties. Discussion: Kodashari Gutika a herbo mineral Formulation, tracing its reference from Sahasrayogam is indicated in various types of fever. Different stages of typhoid fever are corelated to Taruna Jwara, Tapa Jwara and the complicated stage to Sannipataja Jwara. It is studied for its antibacterial effect against Salmonella typhi. However, this study only highlights on the pharmaceutical and analytical aspects of the formulation.

Keywords: Kodashari Gutika, pharmaceutical study, analytical parameters, standardisation.