Abstract

EVALUATION OF IN VITRO ANTI-INFLAMAMTORY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF SAUSSUREA OBVALLATA

Karan D. Atpadkar*, Akanksha N. Mote, Rohit Jadhav, Jogeshwar Sali

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Abstract

Plants are essential to the conventional medicinal framework. Saussurea obvallata is a medicinal plant local to Uttarakhand that has extraordinary cultural and medicinal value. It may be found in the Himalayan zone at high elevations of 3000- 4800 meters.[1] Various research on phytochemical components and their traditional utilize have been distributed, illustrating their therapeutic benefits. All of the accessible information approximately the traditional and regional utilization of Brahma Kamal are included in this manuscript.[1,2] To assess anti inflammatory activity of Saussurea obvallata by in- vitro methods. Phytochemical screening where perform according to standard convention. The anti inflammatory activity of extract (methanol) where inspected using by utilizing protein denaturation test and HRBC membrane stabilizing test. According to WHO report, expanding request of medicinal plants is expected to reach 5 trillion by the year 2050 in international market. So there are different opportunities for pharmaceutical industry. Inflammation is a biological response of the immune system that can be activated by a assortment of variables, counting pathogens, damaged cells and harmful compounds. These factors may initiate acute and/or chronic inflammatory reactions in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease.

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