Abstract

EVALUTION AND FORMULATION TOPICAL HERBAL GEL FOR SKIN

Aditi Sanjay Kumavt*, Pathan N. Hakimkhan, Punam B. Mahanor and Mayuri R. Mandlik

Abstract

Topical herbal gels have emerged as effective alternatives for skin care, combining the therapeutic benefits of natural ingredients with advanced formulation techniques. This review evaluates the formulation processes and the physicochemical, biological, and clinical assessment methods for herbal gels. Key herbal ingredients such as aloe era, glycerine, Turmeric, and Tea Tree Oil are analysed for their properties andefficacy in treating various skin conditions. The review discusses the importance of selecting appropriate gelling agents, optimizing pH levels, and conducting stability tests to ensure product safety and effectiveness. Clinical trials underscore the potential of these gels in managing conditions like acne, inflammation, and irritation. This paper aims to provide a comprehensive understanding of topical herbal gels, promoting their integration into conventional dermatological practice. The prepared gel was tested for its physical appearance, pH, how easily it spreads, thickness (Viscosity), and overall smoothness. It was also tested on rabbits to check for skin irritation and on human volunteers for its effectiveness on cracked heels. Stability studies were done following ICH guidelines. The results showed that the gel looked good, was smooth, and spread easily. Its thickness was between 4200 and 4500 centipoises. No skin irritation was found in the animals. The gel also successfully reduced the number and size of pimples during a two-week study and helped heal cracked heels in human volunteers. Additionally, it was helpful for treating skin rashes, swelling, and skin cracks. It can equally important to skin.

Keywords: Herbal gel, Cow urine, Aloe Vera, Neem, Turmeric, Rose water, Glycerine.