Abstract

REVIEW ON “FAST-DISSOLVING DRUG DELIVERY SYSTEMS: A FOCUS ON AZELNIDIPINE FOR HYPERTENSIVE PATIENTS”

Saily A. Ukharde*, Parag D. Kothawade, Dr. Prashant S. Malpure and Dr. Gokul S. Talele

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Abstract

The review focuses on the use of Fast-Dissolving Drug Delivery Systems (FDDs) to administer azelnidipine to patients with hypertension. FDDs are designed to dissolve quickly in the mouth, which improves patient compliance, especially for those who have trouble swallowing. The calcium channel blocker azelnidipine is used to treat hypertension; its formulation dissolves quickly, resulting in better patient results. This paper examines the many aspects of FDDs, including formulation methods, advantages over traditional administration methods, and their role in enhancing the stability and bioavailability of azelnidipine. It also discusses the challenges that FDDs present, such as taste masking and maintaining the effectiveness of the medication. All things considered, FDDs offer a viable way to improve azelnidipine-assisted hypertension treatment.

Keywords: Fast-dissolving drug delivery systems, Azelnidipine, Bioavailability, Formulation Methods, Taste Masking, Antihypertensive Therapy.