Abstract

PHARMACEUTICAL AND ANALYTICAL STUDY OF ANILARI RASA – A KHARLEEYA RASAYANA

Dr. Shehraz Pasha, Dr. Surekha. S. Medikeri

Abstract

Background: Anilari Rasa is a distinctive herbo-mineral formulation mentioned in Rasaratna Sammuchaya in the context of Amavata. It is classified under kharaleeya rasayana. Pharmaceutical and analytical standardization of Anilari Rasa has not been carried out yet, hence this study aims to focus on its preparation and analytical evaluation. Materials & Methods: Authentic raw materials were selected and evaluated according to classical Grahya Lakshana and Anilari Rasa was prepared according to the classical reference. Organoleptic, Physico-chemical and Instrumental analysis were conducted for Anilari Rasa. Results: Anilari Rasa analysis showed pH-4.09, Loss on Drying LOD-12.06% w/w, Total Ash- 3.95% w/w, Acid Insoluble Ash-0.381% w/w, Water Soluble Ash- 3.09% w/w. Average weight- 363mg, Disintegration time- 47 mins, Water soluble extractive- 31.83%, Alcohol soluble extractive- 22.68% and Friability-0.139%. TLC (Thin Layer Chromatography) showed 3 spots at Rf -0.2,0.3, 0.75. FT-IR (Fourier Transform Infrared Spectroscopy) demonstrated the presence of different organic functional groups such as phenols, carboxylic acid, sulfonamides, aromatic compounds, etc.

Keywords: Anilari Rasa, Kharaleeya Rasayana, Physico-Chemical Analysis, Instrumental Analysis.