Abstract

A REVIEW ON THE ROLE OF GARAVISHA CHIKITSA IN THE MANAGEMENT OF DRUG INDUCED LIVER DISEASES W.S.R TO BILWADI AGADA

*Dr. Jayalakshmi K. M., Dr. Varsha R. Solanki and Dr. Sushant Sud

Abstract

Introduction: Liver diseases accounts for approximately 2 million deaths worldwide out of which 18.3% happens in India. Since liver is the primary organ for metabolism of drugs and other metabolites, exposure to chemicals by means of food, drugs etc. leads to liver injury. During organogenesis, Yakrit is considered to be formed from Rakta. Gara Visha results in Agnimandya, leading to improper Dhatuparinama. The subsequent Rakta Dhatu dushti is the main reason of Yakrit Roga which is one among the symptom of Garavisha. The Srotovaigunya which manifests in Yakrit as inflammatory changes by repeated exposure to chemicals and toxins, infections etc. can be cured with Agada yogas, especially formulations with Garavishahara property. Materials and methods: Bruhatrayee, Keraliya Vishachikitsa Granthas and published articles on Garavisha and Bilwadi Agada were referred. Results: Alpagni is a major symptom of Gara Visha. As a result, Ama Sanchaya occurs and the Dhatuparinama will be affected. Bilwadi Agada is mentioned by Acharya Vagbhata. It is indicated in the treatment of Gara visha, Vishuchika, Ajirna and Jwara. Hence, the drug is effective in correcting the Agni Vaishamya and Garavishajanya Yakritroga. Discussion: Correcting Agni is the first line of management in liver diseases. Garavishahara Chikitsa can remove the Srotovaigunya in Yakrit thereby bringing it back to normalcy. Bilwadi Agada contains 13 drugs and the hepatoprotective activity of Bilwadi Agada is proven against various hepatotoxic agents. Basta Mutra is the Bhavana Dravya of Bilwadi Agada which helps in penetrating the channels and remove the Srotosanga in liver pathologies. In this paper, a conceptual study is proposed to evaluate the effect of Bilwadi Agada in liver disorders.

Keywords: Garavisha, Yakrit, Garavisha janya Yakrit vikara, Agada Yogas, Bilwadi Agada