Abstract

ORODISPERSIBLE TABLETS: A REVOLUTIONARY APPROACH TO ORAL DRUG DELIVERY– A REVIEW

Yogita Prajapati* and Aparajita Patil

Abstract

The oral route remains the most widely used and convenient method for drug administration, offering various dosage forms such as tablets, capsules, syrups, suspensions, and elixirs. However, certain patient populations—including children, the elderly, and bedridden individuals—often face challenges in swallowing conventional solid dosage forms. To overcome these limitations, researchers have developed orodispersible tablets (ODTs), an innovative drug delivery system designed to dissolve quickly in the mouth without the need for water. Orodispersible tablets enhance patient compliance, particularly in populations with swallowing difficulties, while also improving drug bioavailability and ensuring faster onset of action. Their convenience allows administration anytime and anywhere, making them an ideal alternative to traditional formulations. The production of ODTs involves various advanced techniques, including tablet molding, spray drying, freeze drying, sublimation, and mass extrusion, alongside newly developed patented technologies. These methods ensure the rapid disintegration and effective drug release of ODTs, making them a preferred choice in modern pharmaceutical formulations.

Keywords: Orodispersible tablets, Rapid disintegration, Drug bioavailability, Patientfriendly dosage forms, Advanced formulation techniques.