Abstract

THERAPEUTIC POTENTIAL OF BRASSICA OLERACEA VAR. BOTRYTIS: A COMPREHENSIVE REVIEW

Karimulla Baig*, Krishnaveni Mannubolu, Deepthi Singh Krishnagiri, Sai Prathap Reddy Nallapareddy, Lakshmi Prasanna Puchalapalli, Himabindu Sangapu and Sreenivasulu Munna

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Abstract

Cauliflower (Brassica oleracea var. botrytis), a cruciferous vegetable, is a rich source of bioactive compounds with significant antiinflammatory properties. Chronic inflammation, a key factor in the progression of various diseases such as cardiovascular, metabolic, and autoimmune disorders, can be mitigated by natural dietary interventions. The bioactive constituents of cauliflower, including glucosinolates and omega-3 fatty acids, contribute to its antiinflammatory effects through molecular mechanisms such as the activation of the Nrf2 pathway and the modulation of inflammatory mediators. Glucosinolates, upon hydrolysis, release sulforaphane, which enhances antioxidant defenses and reduces oxidative stress, while alpha-linolenic acid (ALA), an omega-3 fatty acid, promotes the production of anti-inflammatory eicosanoids. These mechanisms underscore cauliflower's potential as a functional food for managing inflammation-related diseases. This review explores the molecular pathways through which cauliflower exerts its anti-inflammatory effects, highlighting its therapeutic relevance in chronic disease prevention and management.

Keywords: Cauliflower, Brassica oleracea var. botrytis, Anti-inflammatory, Glucosinolates, Sulforaphane.