Abstract

BIOCHEMICAL, HAEMATOLOGICAL AND HISTOLOGICAL STUDIES ON AQUEOUS LEAF EXTRACTS OF SPINACIA OLERACEA

*Onwusonye Josephat Chukwudi, PhD

Abstract

The present study was conducted to evaluate the effect of aqueous leaf extracts of Spinacia oleracea on haemoglobin (Hb), Packed cell volume (PCV), blood sugar, serum urea and pancreatic cellular integrity in albino rats, Twenty (20) healthy rats were randomly divided into five groups, 1-5 (n=4). Group 1 served as normal control rats kept on feed and water only while groups 2-5 served as treatment groups that received 200 mg/kg, 400 mg/kg, 600 mg/kg, and 800 mg/kg respectively of the extract daily for 3 weeks. Hematological investigations revealed a dose-dependent increase in Hb concentration and PCV, with the highest dose (800 mg/kg) yielding the most significant improvements (p

Keywords: Biochemical, haematological, histological, spinacia oleracea.