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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
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Dr. Dhrubo Jyoti Sen
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Abstract

THE ROLE OF NATURAL INGREDIENTS IN TREATING HYPERLIPIDEMIA: A BREAKTHROUGH STUDY

Kosuri Bharath Karthik Varma, Kota Pragna Sri, Meda Mohan Sai, Kallem Chandu

Priya, Nagineni Sudarshan Rao*

Abstract

Hyperlipidemia, characterized by elevated levels of lipids (cholesterol and triglycerides) in the blood, is a significant risk factor for cardiovascular diseases, including atherosclerosis, stroke, and heart attack. Traditional pharmacological treatments for hyperlipidemia, such as statins, have been effective but are often associated with side effects, leading to a growing interest in alternative therapies. In recent years, natural ingredients derived from plants, herbs, and other natural sources have gained attention for their potential in managing hyperlipidemia. This breakthrough study explores the role of these natural ingredients in the treatment and management of hyperlipidemia, focusing on their mechanisms of action, efficacy, and safety. A comprehensive review of the literature was conducted to identify key natural substances with proven lipid-lowering effects, including flavonoids, polyphenols, alkaloids, and unsaturated fatty acids. The study highlights the role of compounds such as turmeric (curcumin), garlic (allicin), ginger, omega-3 fatty acids, and green tea catechins in reducing total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides while increasing high-density lipoprotein (HDL) cholesterol. Mechanistically, these natural ingredients act through various pathways, including antioxidant properties, inhibition of cholesterol synthesis, modulation of lipid metabolism enzymes, and improvement of lipid profiles through anti-inflammatory effects. The study also presents clinical trial data supporting the efficacy of these natural ingredients, with many studies demonstrating significant improvements in lipid profiles without the adverse effects commonly seen with pharmaceutical interventions. Furthermore, the safety and bioavailability of these ingredients, as well as their potential for integration into dietary practices, are discussed. This research concludes that natural ingredients represent a promising, low-risk approach for managing hyperlipidemia, offering a complementary treatment strategy alongside conventional therapies. In summary; natural ingredients hold substantial potential in the treatment of hyperlipidemia, providing an effective, holistic approach for cardiovascular health management.

Keywords: Cholesterol management, Lipid lowering therapy, Cardio protective agents, Sustainable healthcare solutions, hyperlipidemia symptoms, hyperlipidemia medication, recommendations for hyperlipidemia.


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