Abstract

AN OPEN LABELLED RANDOMISED CONTROLLED CLINICAL TRIAL ON THE EFFECT OF SHUDDHA SHILAJATU IN DYSLIPIDEMIA

Venupriya Mishra* and Shrilatha Kamath T.

Abstract

Dyslipidemia has attracted global attention due to its role in the pathology of atherosclerotic diseases, particularly coronary heart disease, which is the leading cause of death and illness worldwide. Disorders in lipoprotein metabolism are collectively known as dyslipidemia, characterized by elevated plasma levels of cholesterol and triglycerides, often accompanied by decreased levels of HDL cholesterol. Objective: To evaluate the effect of Shuddha Shilajatu on serum lipid profile in patients of Dyslipidemia. Methodology: An open-label controlled clinical study with a pre- and post-test design involved 30 patients with elevated lipid profiles from Sri Dharmasthala Manjunatheshwara Ayurveda Hospital, Udupi. Patients were randomly divided into two groups: Group A (control) received 6 capsules of Shuddha Guggulu twice daily before meals, while Group B (study) received 2 capsules of Shuddha Shilajatu twice daily before meals for 30 days. Assessments were based on primary and secondary outcome measures, focusing on changes in lipid profile parameters and SF-36 Health Survey Scores before and after treatment. Results: Among the patients in Group-A, 7% of patients reported excellent improvement, 40% experienced good improvement and 33% noted moderate improvement. In Group-B 46.66% showed moderate improvement and 33.33% demonstrated mild improvement. Conclusion: Group-A showed considerably more relief and improvement than Group-B across multiple metrics, with no significant statistical differences observed.

Keywords: Dyslipidemia, Shonita abhishyanda, Shilajatu, Guggulu.