Abstract

A MINI REVIEW ON MANGIFERIN INDICA (MANGO)

Harsha Vardhan*, D. Abhilasha, I. Supriya, G. Naga Praveen and R. Revanth

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Abstract

Mangiferin is a bio active substance primarily extracted from the mango tree, mangiferin (1,3,6,7-tetra hydroxyxanthon-C2-beta-DGlucoside) has strong anti-oxidant activity and a variety of pharmacological effects, such as anti tumour, neuroprotective, antioxident, anti-inflammatory, anti-diabetic, anti-viral and immunomodulatory as a result it has a number of health promoting qualities and is a good option for additional study and advancement the development of mangiferin as a clinical treatment is, however limited by its low solubility ,mucosal permeability and bio availability in order to increase its use, chemical and physical modification are needed. It inhibits the activation of peroxisome proliferator activated receptor isoforms via altering the transcription process mangiferin suppresses tumor necrosis factor alpha expression inducible nitric oxide synthase potential, proliferation and induces apoptosis to protect against many human malignancies such as lung, colon, breast and neural.

Keywords: Bio active molecules, Human cancers, Mangiferin, Nutrition, Health claims, Toxicity.