Abstract

FORMULATION AND EVALUATION OF ANTIMICROBIAL CREAM OF AZADIRACHTA INDICA

Sahil Narwade*, Prerna Narwade, Harshal Ovhal, Rutuja Pardeshi,

Abstract

In the pharmaceutical market, various dosage forms are designed and introduced to cater to patient needs, improve compliance, and offer faster relief. While each dosage form possesses unique advantages, they also come with certain limitations. Historically, drugs have been administered to the human body through numerous routes, including oral, sublingual, rectal, parenteral, topical, inhalation, and others. Among these, topical delivery, particularly through creams, is considered superior for skin-related conditions. Topical delivery involves applying a drug-containing formulation directly to the skin to treat cutaneous disorders or systemic diseases that manifest on the skin (e.g., psoriasis). The goal is to localize the drug's effect to the skin's surface or deeper layers. Although creams are the predominant topical delivery system, other formulations such as medicated sprays, powders, solutions, and adhesive systems are also commonly used.

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