Abstract

FORMULATION AND EVALUATION OF MELOXICAM EMULGEL DELIVERY SYSTEM FOR TOPICAL APPLICATIONS

Mahmoud Mahyoob Alburyhi*, Maged Alwan Noman and Abdalwali Ahmed Saif

Abstract

Meloxicam emulgel is a topical formulation that contains the nonsteroidal anti-inflammatory drug (NSAID) Meloxicam. It is used for the treatment of pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis Emulgels are the result of combining the terms emulsion and gel. It has a number of features, including enhanced permeability and strong thermodynamic stability. These are either water in oil emulsion or oil in water emulsion, by combining it with a gelling agent, it became gelled Emulgel offers a dual control and a long-lasting release and patient compliance. Five formulas were prepared and the evaluation of Meloxicam emulgel involves assessing its physicochemical properties, drug release characteristics and potential therapeutic effects. It was concluded that, F1 is the best formula for formulation of Meloxicam Emulgel when compared to other formulations.

Keywords: Meloxicam, Formulation, Emulgels.