Abstract

DESIGN, SYNTHESIS AND CHARACTERISATION OF SILVER NANOPARTICALS (ANDROGRAPHIS ECHIOIDES)

J. Aruna*, Manikandan P., Pragathi S., Prathiksha S., Priya R., Ragul M. and Saraswathy M.

Abstract

An environmentally friendly method of producing silver nanoparticles (AgNPs) with the ethanolic extract of Andrographis echioides. During manufacture, silver nanoparticles were found using UV and other analytical techniques. The produced AgNPs were evaluated for their in-vitro anti-inflammatory and anti-oxidant properties utilizing a protein denaturation assay with diclofenac sodium as standard and ascorbic acid (vitamin C) as standard in DPPH. Maximum absorption at 400–45nm indicates AgNP generation, and biosynthesis validates the color shift from colorless to reddish brown. When compared to standard under identical conditions, AgNPs have notable antiinflammatory and antioxidant properties. These in vitro studies demonstrate the need for more studies on phytochemicals in order to increase their biological activity.

Keywords: Andrographis echioides, antioxidant, DPPH assay, anti-inflammatory, silver nanoparticle AgNps, UV.