Abstract

DESIGN, SYNTHESIS AND CHARACTERISATION OF SILVER NANOPARTICLES (BRYOPHYLLUM PINNATUM)

J. Aruna*, Manikandan P., Pragathi S., Prathiksha S., Priya R. Ragul M. and Saraswathy M.

Abstract

The production of silver nanoparticle(AgNPs) using an environmentally benign process from the BRYOPHYLLUM PINNATUM plant (family; Crassulaceae). Plant based nanoparticle offer sustainable, Eco-friendly alternatives to conventional methods. UV and other analytical techniques are used to analyze the biosynthesis of silver nanoparticles. Bryophyllum pinnatum is an indigenous and exotic plant used widely by the traditional Practitioner for treating various ailments like renal calculi, hypertension, asthma, cold, bleeding disorders. Prepared silver nanoparticles were examined for in vitro antioxidant activity using DPPH and ascorbic acid [VITAMIN-C] as standard. Additionally, protein denaturation assay was used to test for in vitro anti-inflammatory activity using diclofenac sodium as standard. The production of silver nanoparticles during biosynthesis is confirmed by color shifts from from colourless to reddish brown, with maximal absorption occurring between 400 and 450 nm. Comparing AgNPs to standard under identical settings, they exhibit good anti-inflammatory and considerable antioxidant activity. These in vitro data are suitable for in vivo animal studies. Bryophyllum pinnatum is the good source for the medicinal drug and have the properties of antidiabetic, anti-pyretic etc. Bryophyllum pinnatum were used for fresh utilisation by washing, weighing and crushing their leaves, then mixing them with distilled water and heating at 50℃and 60℃ for 30 mins.

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